We show that a classifier based on Gaussian mixture models (GMM) can be trained discriminatively to improve accuracy. We describe a training procedure based on the extended Baum-W...
Density modeling is notoriously difficult for high dimensional data. One approach to the problem is to search for a lower dimensional manifold which captures the main characteristi...
Mixture models have been widely used for data clustering. However, commonly used mixture models are generally of a parametric form (e.g., mixture of Gaussian distributions or GMM),...
Background: Liquid chromatography-mass spectrometry (LC-MS) is one of the major techniques for the quantification of metabolites in complex biological samples. Peak modeling is on...
The Predictive Linear Gaussian model (or PLG) improves upon traditional linear dynamical system models by using a predictive representation of state, which makes consistent parame...