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BMCBI
2008
106views more  BMCBI 2008»
13 years 5 months ago
SpliceCenter: A suite of web-based bioinformatic applications for evaluating the impact of alternative splicing on RT-PCR, RNAi,
Background: Over 60% of protein-coding genes in vertebrates express mRNAs that undergo alternative splicing. The resulting collection of transcript isoforms poses significant chal...
Michael C. Ryan, Barry Zeeberg, Natasha J. Caplen,...
BMCBI
2010
96views more  BMCBI 2010»
13 years 5 months ago
QTLminer: identifying genes regulating quantitative traits
Background: Quantitative trait locus (QTL) mapping identifies genomic regions that likely contain genes regulating a quantitative trait. However, QTL regions may encompass tens to...
Rudi Alberts, Klaus Schughart
BMCBI
2008
155views more  BMCBI 2008»
13 years 5 months ago
Extending pathways based on gene lists using InterPro domain signatures
Background: High-throughput technologies like functional screens and gene expression analysis produce extended lists of candidate genes. Gene-Set Enrichment Analysis is a commonly...
Florian Hahne, Alexander Mehrle, Dorit Arlt, Annem...
RSFDGRC
2005
Springer
192views Data Mining» more  RSFDGRC 2005»
13 years 11 months ago
An Open Source Microarray Data Analysis System with GUI: Quintet
We address Quintet, an R-based unified cDNA microarray data analysis system with GUI. Five principal categories of microarray data analysis have been coherently integrated in Quin...
Jun-kyoung Choe, Tae-Hoon Chung, Sunyong Park, Hwa...
BMCBI
2006
82views more  BMCBI 2006»
13 years 5 months ago
Transcriptomic response to differentiation induction
Background: Microarrays used for gene expression studies yield large amounts of data. The processing of such data typically leads to lists of differentially-regulated genes. A com...
G. W. Patton, Robert M. Stephens, I. A. Sidorov, X...