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BMCBI
2010
132views more  BMCBI 2010»
13 years 5 months ago
Error margin analysis for feature gene extraction
Background: Feature gene extraction is a fundamental issue in microarray-based biomarker discovery. It is normally treated as an optimization problem of finding the best predictiv...
Chi Kin Chow, Hai Long Zhu, Jessica Lacy, Winston ...
BMCBI
2008
115views more  BMCBI 2008»
13 years 5 months ago
Principal components analysis based methodology to identify differentially expressed genes in time-course microarray data
Background: Time-course microarray experiments are being increasingly used to characterize dynamic biological processes. In these experiments, the goal is to identify genes differ...
Sudhakar Jonnalagadda, Rajagopalan Srinivasan
BMCBI
2004
205views more  BMCBI 2004»
13 years 5 months ago
A combinational feature selection and ensemble neural network method for classification of gene expression data
Background: Microarray experiments are becoming a powerful tool for clinical diagnosis, as they have the potential to discover gene expression patterns that are characteristic for...
Bing Liu, Qinghua Cui, Tianzi Jiang, Songde Ma
BMCBI
2010
96views more  BMCBI 2010»
13 years 5 months ago
A statistical framework for differential network analysis from microarray data
Background: It has been long well known that genes do not act alone; rather groups of genes act in consort during a biological process. Consequently, the expression levels of gene...
Ryan Gill, Somnath Datta, Susmita Datta
BMCBI
2005
121views more  BMCBI 2005»
13 years 5 months ago
Comparison of seven methods for producing Affymetrix expression scores based on False Discovery Rates in disease profiling data
Background: A critical step in processing oligonucleotide microarray data is combining the information in multiple probes to produce a single number that best captures the express...
Kerby Shedden, Wei Chen, Rork Kuick, Debashis Ghos...