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BMCBI
2011
12 years 11 months ago
Motif-guided sparse decomposition of gene expression data for regulatory module identification
Background: Genes work coordinately as gene modules or gene networks. Various computational approaches have been proposed to find gene modules based on gene expression data; for e...
Ting Gong, Jianhua Xuan, Li Chen, Rebecca B. Riggi...
BMCBI
2006
156views more  BMCBI 2006»
13 years 4 months ago
GOFFA: Gene Ontology For Functional Analysis - A FDA Gene Ontology Tool for Analysis of Genomic and Proteomic Data
Background: Gene Ontology (GO) characterizes and categorizes the functions of genes and their products according to biological processes, molecular functions and cellular componen...
Hongmei Sun, Hong Fang, Tao Chen, Roger Perkins, W...
BMCBI
2008
132views more  BMCBI 2008»
13 years 4 months ago
Very Important Pool (VIP) genes - an application for microarray-based molecular signatures
Background: Advances in DNA microarray technology portend that molecular signatures from which microarray will eventually be used in clinical environments and personalized medicin...
Zhenqiang Su, Huixiao Hong, Hong Fang, Leming M. S...
BMCBI
2006
95views more  BMCBI 2006»
13 years 4 months ago
XcisClique: analysis of regulatory bicliques
Background: Modeling of cis-elements or regulatory motifs in promoter (upstream) regions of genes is a challenging computational problem. In this work, set of regulatory motifs si...
Amrita Pati, Cecilia Vasquez-Robinet, Lenwood S. H...
BMCBI
2006
127views more  BMCBI 2006»
13 years 4 months ago
A graph-search framework for associating gene identifiers with documents
Background: One step in the model organism database curation process is to find, for each article, the identifier of every gene discussed in the article. We consider a relaxation ...
William W. Cohen, Einat Minkov