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» Large scale reconstruction of haplotypes from genotype data
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BMCBI
2007
165views more  BMCBI 2007»
13 years 5 months ago
Direct maximum parsimony phylogeny reconstruction from genotype data
Background: Maximum parsimony phylogenetic tree reconstruction from genetic variation data is a fundamental problem in computational genetics with many practical applications in p...
Srinath Sridhar, Fumei Lam, Guy E. Blelloch, R. Ra...
JCB
2006
123views more  JCB 2006»
13 years 5 months ago
Reconstructing Ancestral Haplotypes with a Dictionary Model
We propose a dictionary model for haplotypes. According to the model, a haplotype is constructed by randomly concatenating haplotype segments from a given dictionary of segments. ...
Kristin L. Ayers, Chiara Sabatti, Kenneth Lange
BMCBI
2008
138views more  BMCBI 2008»
13 years 5 months ago
Inference of haplotypic phase and missing genotypes in polyploid organisms and variable copy number genomic regions
Background: The power of haplotype-based methods for association studies, identification of regions under selection, and ancestral inference, is well-established for diploid organ...
Shu-Yi Su, Jonathan White, David J. Balding, Lachl...
AAAI
2006
13 years 6 months ago
Efficient Haplotype Inference with Boolean Satisfiability
One of the main topics of research in genomics is determining the relevance of mutations, described in haplotype data, as causes of some genetic diseases. However, due to technolo...
Inês Lynce, João Marques-Silva
IJAIT
2008
107views more  IJAIT 2008»
13 years 5 months ago
Haplotype Inference with Boolean Satisfiability
One of the main topics of research in genomics is determining the relevance of mutations, described in haplotype data, as causes of some genetic diseases. However, due to technolo...
Inês Lynce, João Marques-Silva