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BMCBI
2010
130views more  BMCBI 2010»
13 years 4 months ago
Amino acid "little Big Bang": Representing amino acid substitution matrices as dot products of Euclidian vectors
Background: Sequence comparisons make use of a one-letter representation for amino acids, the necessary quantitative information being supplied by the substitution matrices. This ...
Karel Zimmermann, Jean-François Gibrat
BMCBI
2010
118views more  BMCBI 2010»
13 years 4 months ago
Walk-weighted subsequence kernels for protein-protein interaction extraction
Background: The construction of interaction networks between proteins is central to understanding the underlying biological processes. However, since many useful relations are exc...
Seonho Kim, Juntae Yoon, Jihoon Yang, Seog Park
BMCBI
2007
126views more  BMCBI 2007»
13 years 4 months ago
High-throughput identification of interacting protein-protein binding sites
Background: With the advent of increasing sequence and structural data, a number of methods have been proposed to locate putative protein binding sites from protein surfaces. Ther...
Jo-Lan Chung, Wei Wang, Philip E. Bourne