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ICCAD
2009
IEEE
147views Hardware» more  ICCAD 2009»
13 years 3 months ago
SAT-based protein design
Computational protein design can be formulated as an optimization problem, where the objective is to identify the sequence of amino acids that minimizes the energy of a given prot...
Noah Ollikainen, Ellen Sentovich, Carlos Coelho, A...
IJON
2010
121views more  IJON 2010»
13 years 3 months ago
Sample-dependent graph construction with application to dimensionality reduction
Graph construction plays a key role on learning algorithms based on graph Laplacian. However, the traditional graph construction approaches of -neighborhood and k-nearest-neighbor...
Bo Yang, Songcan Chen
BMCBI
2010
172views more  BMCBI 2010»
13 years 23 days ago
Nonparametric identification of regulatory interactions from spatial and temporal gene expression data
Background: The correlation between the expression levels of transcription factors and their target genes can be used to infer interactions within animal regulatory networks, but ...
Anil Aswani, Soile V. E. Keränen, James Brown...
BMCBI
2011
13 years 23 days ago
NClassG+: A classifier for non-classically secreted Gram-positive bacterial proteins
Background: Most predictive methods currently available for the identification of protein secretion mechanisms have focused on classically secreted proteins. In fact, only two met...
Daniel Restrepo-Montoya, Camilo Pino, Luis F. Ni&n...
BMCBI
2011
13 years 23 days ago
A comparison and user-based evaluation of models of textual information structure in the context of cancer risk assessment
Background: Many practical tasks in biomedicine require accessing specific types of information in scientific literature; e.g. information about the results or conclusions of the ...
Yufan Guo, Anna Korhonen, Maria Liakata, Ilona Sil...