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BMCBI
2006
115views more  BMCBI 2006»
13 years 5 months ago
Multivariate curve resolution of time course microarray data
Background: Modeling of gene expression data from time course experiments often involves the use of linear models such as those obtained from principal component analysis (PCA), i...
Peter D. Wentzell, Tobias K. Karakach, Sushmita Ro...
BMCBI
2010
97views more  BMCBI 2010»
13 years 5 months ago
Kinome-wide interaction modelling using alignment-based and alignment-independent approaches for kinase description and linear a
Background: Protein kinases play crucial roles in cell growth, differentiation, and apoptosis. Abnormal function of protein kinases can lead to many serious diseases, such as canc...
Maris Lapinsh, Jarl E. S. Wikberg
CIBB
2008
13 years 7 months ago
Unsupervised Stability-Based Ensembles to Discover Reliable Structures in Complex Bio-molecular Data
The assessment of the reliability of clusters discovered in bio-molecular data is a central issue in several bioinformatics problems. Several methods based on the concept of stabil...
Alberto Bertoni, Giorgio Valentini
SIGMOD
2005
ACM
136views Database» more  SIGMOD 2005»
14 years 5 months ago
Peer-to-peer management of XML data: issues and research challenges
Peer-to-peer (p2p) systems are attracting increasing attention as an efficient means of sharing data among large, diverse and dynamic sets of users. The widespread use of XML as a...
Georgia Koloniari, Evaggelia Pitoura
ISPW
1994
IEEE
13 years 9 months ago
Issues in process architecture
I consider the problems of process system architecture in the context of the Perry-Wolf model of software architecture: process elements are executed in process systems by both ma...
Dewayne E. Perry