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» Logical Development of the Cell Ontology
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BMCBI
2010
115views more  BMCBI 2010»
13 years 5 months ago
Multiconstrained gene clustering based on generalized projections
Background: Gene clustering for annotating gene functions is one of the fundamental issues in bioinformatics. The best clustering solution is often regularized by multiple constra...
Jia Zeng, Shanfeng Zhu, Alan Wee-Chung Liew, Hong ...
BMCBI
2008
135views more  BMCBI 2008»
13 years 5 months ago
Knowledge-guided multi-scale independent component analysis for biomarker identification
Background: Many statistical methods have been proposed to identify disease biomarkers from gene expression profiles. However, from gene expression profile data alone, statistical...
Li Chen, Jianhua Xuan, Chen Wang, Ie-Ming Shih, Yu...
BMCBI
2007
148views more  BMCBI 2007»
13 years 5 months ago
Computation of significance scores of unweighted Gene Set Enrichment Analyses
Background: Gene Set Enrichment Analysis (GSEA) is a computational method for the statistical evaluation of sorted lists of genes or proteins. Originally GSEA was developed for in...
Andreas Keller, Christina Backes, Hans-Peter Lenho...
BMCBI
2005
153views more  BMCBI 2005»
13 years 5 months ago
Mining published lists of cancer related microarray experiments: Identification of a gene expression signature having a critical
Background: Routine application of gene expression microarray technology is rapidly producing large amounts of data that necessitate new approaches of analysis. The analysis of a ...
Giacomo Finocchiaro, Francesco Mancuso, Heiko M&uu...
AISADM
2005
Springer
13 years 11 months ago
Evolving Agents: Communication and Cognition
Computer programming of complex systems is a time consuming effort. Results are often brittle and inflexible. Evolving, self-learning flexible multi-agent systems remain a distant ...
Leonid I. Perlovsky