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» Machine learning methods for metabolic pathway prediction
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SAC
2006
ACM
13 years 11 months ago
Protein classification using transductive learning on phylogenetic profiles
Phylogenetic profiles of proteins − strings of ones and zeros encoding respectively the presence and absence of proteins in a group of genomes − have recently been used to iden...
Roger A. Craig, Li Liao
GECCO
2005
Springer
124views Optimization» more  GECCO 2005»
13 years 11 months ago
Evolving petri nets to represent metabolic pathways
Given concentrations of metabolites over a sequence of time steps, the metabolic pathway prediction problem seeks a set of reactions and rate constants for them that could yield t...
Jeremiah Nummela, Bryant A. Julstrom
GCB
2010
Springer
204views Biometrics» more  GCB 2010»
13 years 3 months ago
Learning Pathway-based Decision Rules to Classify Microarray Cancer Samples
: Despite recent advances in DNA chip technology current microarray gene expression studies are still affected by high noise levels, small sample sizes and large numbers of uninfor...
Enrico Glaab, Jonathan M. Garibaldi, Natalio Krasn...
BMCBI
2006
127views more  BMCBI 2006»
13 years 5 months ago
Construction of phylogenetic trees by kernel-based comparative analysis of metabolic networks
Background: To infer the tree of life requires knowledge of the common characteristics of each species descended from a common ancestor as the measuring criteria and a method to c...
Sok June Oh, Je-Gun Joung, Jeong Ho Chang, Byoung-...
BMCBI
2010
86views more  BMCBI 2010»
13 years 5 months ago
Reaction graph kernels predict EC numbers of unknown enzymatic reactions in plant secondary metabolism
Background: Understanding of secondary metabolic pathway in plant is essential for finding druggable candidate enzymes. However, there are many enzymes whose functions are not yet...
Hiroto Saigo, Masahiro Hattori, Hisashi Kashima, K...