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» Machine learning of functional class from phenotype data
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BIOINFORMATICS
2002
61views more  BIOINFORMATICS 2002»
13 years 5 months ago
Machine learning of functional class from phenotype data
Amanda Clare, Ross D. King
PKDD
2001
Springer
108views Data Mining» more  PKDD 2001»
13 years 9 months ago
Knowledge Discovery in Multi-label Phenotype Data
The biological sciences are undergoing an explosion in the amount of available data. New data analysis methods are needed to deal with the data. We present work using KDD to analys...
Amanda Clare, Ross D. King
BMCBI
2010
105views more  BMCBI 2010»
13 years 5 months ago
Predicting phenotypic traits of prokaryotes from protein domain frequencies
Background: Establishing the relationship between an organism's genome sequence and its phenotype is a fundamental challenge that remains largely unsolved. Accurately predict...
Thomas Lingner, Stefanie Mühlhausen, Toni Gab...
BMCBI
2010
179views more  BMCBI 2010»
13 years 5 months ago
A semi-supervised learning approach to predict synthetic genetic interactions by combining functional and topological properties
Background: Genetic interaction profiles are highly informative and helpful for understanding the functional linkages between genes, and therefore have been extensively exploited ...
Zhuhong You, Zheng Yin, Kyungsook Han, De-Shuang H...
BMCBI
2007
127views more  BMCBI 2007»
13 years 5 months ago
Predicting the phenotypic effects of non-synonymous single nucleotide polymorphisms based on support vector machines
Background: Human genetic variations primarily result from single nucleotide polymorphisms (SNPs) that occur approximately every 1000 bases in the overall human population. The no...
Jian Tian, Ningfeng Wu, Xuexia Guo, Jun Guo, Juhua...