18 search results - page 1 / 4 » Major copy proportion analysis of tumor samples using SNP ar... |
BMCBI
2008
13 years 4 months ago
2008
Background: Single nucleotide polymorphisms (SNPs) are the most common genetic variations in the human genome and are useful as genomic markers. Oligonucleotide SNP microarrays ha...
BMCBI
2008
13 years 4 months ago
2008
Background: Illumina Infinium whole genome genotyping (WGG) arrays are increasingly being applied in cancer genomics to study gene copy number alterations and allele-specific aber...
BMCBI
2006
13 years 4 months ago
2006
Background: DNA copy number alterations are one of the main characteristics of the cancer cell karyotype and can contribute to the complex phenotype of these cells. These alterati...
BMCBI
2010
13 years 4 months ago
2010
Background: DNA copy number aberration (CNA) is very important in the pathogenesis of tumors and other diseases. For example, CNAs may result in suppression of anti-oncogenes and ...
BMCBI
2007
13 years 4 months ago
2007
Background: Affymetrix SNP arrays can interrogate thousands of SNPs at the same time. This allows us to look at the genomic content of cancer cells and to investigate the underlyi...