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    BMCBI
    2010
    178views more  BMCBI 2010»
    CNV Workshop: an integrated platform for high-throughput copy number variation discovery and clinical diagnostics
    13 years 5 months ago
    CNV Workshop: an integrated platform for high-throughput copy number variation discovery and clinical diagnostics
    Download  www.biomedcentral.com
    Background: Recent studies have shown that copy number variations (CNVs) are frequent in higher eukaryotes and associated with a substantial portion of inherited and acquired risk...
    Xiaowu Gai, Juan C. Perin, Kevin Murphy, Ryan O'Ha...
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    BIOINFORMATICS
    2010
    170views more  BIOINFORMATICS 2010»
    Joint estimation of DNA copy number from multiple platforms
    13 years 5 months ago
    Joint estimation of DNA copy number from multiple platforms
    Download  www-stat.stanford.edu
    DNA copy number variants (CNV) are gains and losses of segments of chromosomes, and comprise an important class of genetic variation. Recently, various microarray hybridization ba...
    Nancy R. Zhang, Yasin Senbabaoglu, Jun Z. Li
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    BMCBI
    2011
    221views Artificial Intelligence» more  BMCBI 2011»
    Wavelet-based identification of DNA focal genomic aberrations from single nucleotide polymorphism arrays
    12 years 8 months ago
    Wavelet-based identification of DNA focal genomic aberrations from single nucleotide polymorphism arrays
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    Background: Copy number aberrations (CNAs) are an important molecular signature in cancer initiation, development, and progression. However, these aberrations span a wide range of...
    Youngmi Hur, Hyunju Lee
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    BMCBI
    2011
    219views Artificial Intelligence» more  BMCBI 2011»
    Genotype calling in tetraploid species from bi-allelic marker data using mixture models
    12 years 8 months ago
    Genotype calling in tetraploid species from bi-allelic marker data using mixture models
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    Background: Automated genotype calling in tetraploid species was until recently not possible, which hampered genetic analysis. Modern genotyping assays often produce two signals, ...
    Roeland E. Voorrips, Gerrit Gort, Ben Vosman
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    BMCBI
    2007
    104views more  BMCBI 2007»
    A response to Yu et al. "A forward-backward fragment assembling algorithm for the identification of genomic amplification and de
    13 years 4 months ago
    A response to Yu et al. "A forward-backward fragment assembling algorithm for the identification of genomic amplification and de
    Download  www.biomedcentral.com
    Background: Yu et al. (BMC Bioinformatics 2007,8: 145+) have recently compared the performance of several methods for the detection of genomic amplification and deletion breakpoin...
    Oscar M. Rueda, Ramón Díaz-Uriarte
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