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BMCBI
2007
148views more  BMCBI 2007»
13 years 6 months ago
WeederH: an algorithm for finding conserved regulatory motifs and regions in homologous sequences
Background: This work addresses the problem of detecting conserved transcription factor binding sites and in general regulatory regions through the analysis of sequences from homo...
Giulio Pavesi, Federico Zambelli, Graziano Pesole
BMCBI
2010
160views more  BMCBI 2010»
13 years 6 months ago
Annotation of gene promoters by integrative data-mining of ChIP-seq Pol-II enrichment data
Background: Use of alternative gene promoters that drive widespread cell-type, tissue-type or developmental gene regulation in mammalian genomes is a common phenomenon. Chromatin ...
Ravi Gupta, Priyankara Wikramasinghe, Anirban Bhat...
BMCBI
2010
120views more  BMCBI 2010»
13 years 6 months ago
Modeling expression quantitative trait loci in data combining ethnic populations
Background: Combining data from different ethnic populations in a study can increase efficacy of methods designed to identify expression quantitative trait loci (eQTL) compared to...
Ching-Lin Hsiao, Ie-Bin Lian, Ai-Ru Hsieh, Cathy S...
BMCBI
2008
129views more  BMCBI 2008»
13 years 6 months ago
Motif-directed network component analysis for regulatory network inference
Background: Network Component Analysis (NCA) has shown its effectiveness in discovering regulators and inferring transcription factor activities (TFAs) when both microarray data a...
Chen Wang, Jianhua Xuan, Li Chen, Po Zhao, Yue Wan...
BMCBI
2005
122views more  BMCBI 2005»
13 years 6 months ago
Finding genomic ontology terms in text using evidence content
Background: The development of text mining systems that annotate biological entities with their properties using scientific literature is an important recent research topic. These...
Francisco M. Couto, Mário J. Silva, Pedro C...