Ascertaining the similarity amongst molecules is a fundamental problem in biology and drug discovery. Since similar molecules tend to have similar biological properties, the notio...
Background: A gene-regulatory network (GRN) refers to DNA segments that interact through their RNA and protein products and thereby govern the rates at which genes are transcribed...
Martin T. Swain, Johannes J. Mandel, Werner Dubitz...
The Dynamic Execution Layer Interface (DELI) offers the following unique capability: it provides fine-grain control over the execution of programs, by allowing its clients to obse...
Giuseppe Desoli, Nikolay Mateev, Evelyn Duesterwal...
Background: The use of exogenous small interfering RNAs (siRNAs) for gene silencing has quickly become a widespread molecular tool providing a powerful means for gene functional s...
Jean-Philippe Vert, Nicolas Foveau, Christian Laja...
Proper scoring rules, particularly when used as the basis for a prediction market, are powerful tools for eliciting and aggregating beliefs about events such as the likely outcome...