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BMCBI
2008
136views more  BMCBI 2008»
13 years 5 months ago
A comparison of machine learning algorithms for chemical toxicity classification using a simulated multi-scale data model
Background: Bioactivity profiling using high-throughput in vitro assays can reduce the cost and time required for toxicological screening of environmental chemicals and can also r...
Richard Judson, Fathi Elloumi, R. Woodrow Setzer, ...
ICSE
2008
IEEE-ACM
14 years 5 months ago
Predicting defects using network analysis on dependency graphs
In software development, resources for quality assurance are limited by time and by cost. In order to allocate resources effectively, managers need to rely on their experience bac...
Thomas Zimmermann, Nachiappan Nagappan
BMCBI
2008
145views more  BMCBI 2008»
13 years 5 months ago
The contrasting properties of conservation and correlated phylogeny in protein functional residue prediction
Background: Amino acids responsible for structure, core function or specificity may be inferred from multiple protein sequence alignments where a limited set of residue types are ...
Jonathan R. Manning, Emily R. Jefferson, Geoffrey ...
BMCBI
2008
152views more  BMCBI 2008»
13 years 5 months ago
Predicting biological system objectives de novo from internal state measurements
Background: Optimization theory has been applied to complex biological systems to interrogate network properties and develop and refine metabolic engineering strategies. For examp...
Erwin P. Gianchandani, Matthew A. Oberhardt, Antho...
HUC
2010
Springer
13 years 6 months ago
Bridging the gap between physical location and online social networks
This paper examines the location traces of 489 users of a location sharing social network for relationships between the users' mobility patterns and structural properties of ...
Justin Cranshaw, Eran Toch, Jason I. Hong, Aniket ...