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BMCBI
2010
118views more  BMCBI 2010»
13 years 5 months ago
Testing for mean and correlation changes in microarray experiments: an application for pathway analysis
Background: Microarray experiments examine the change in transcript levels of tens of thousands of genes simultaneously. To derive meaningful data, biologists investigate the resp...
Mayer Alvo, Zhongzhu Liu, Andrew Williams, Carole ...
BMCBI
2005
114views more  BMCBI 2005»
13 years 4 months ago
Signal transduction pathway profiling of individual tumor samples
Background: Signal transduction pathways convey information from the outside of the cell to transcription factors, which in turn regulate gene expression. Our objective is to anal...
Thomas Breslin, Morten Krogh, Carsten Peterson, Ca...
BMCBI
2006
138views more  BMCBI 2006»
13 years 5 months ago
Determination of strongly overlapping signaling activity from microarray data
Background: As numerous diseases involve errors in signal transduction, modern therapeutics often target proteins involved in cellular signaling. Interpretation of the activity of...
Ghislain Bidaut, Karsten Suhre, Jean-Michel Claver...
BMCBI
2005
189views more  BMCBI 2005»
13 years 4 months ago
Quantitative inference of dynamic regulatory pathways via microarray data
Background: The cellular signaling pathway (network) is one of the main topics of organismic investigations. The intracellular interactions between genes in a signaling pathway ar...
Wen-Chieh Chang, Chang-Wei Li, Bor-Sen Chen
FSKD
2006
Springer
127views Fuzzy Logic» more  FSKD 2006»
13 years 8 months ago
On the Society of Genome: Social Affiliation Network Analysis of Microarray Data
Abstract. To investigate the structure of the genomic interaction network built from yeast gene-expression compendium dataset of hundreds of systematic perturbations, social affili...
Jung Hun Ohn, Jihoon Kim, Ju Han Kim