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BMCBI
2011
12 years 11 months ago
Motif-guided sparse decomposition of gene expression data for regulatory module identification
Background: Genes work coordinately as gene modules or gene networks. Various computational approaches have been proposed to find gene modules based on gene expression data; for e...
Ting Gong, Jianhua Xuan, Li Chen, Rebecca B. Riggi...
ICASSP
2011
IEEE
12 years 8 months ago
Biological pathway inference using manifold embedding
Disease occurs due to aberrant modulation of biological pathways. Identification of activated gene pathways from gene expression data is an important problem. In this work, we de...
Arvind Rao, Alfred O. Hero
GPB
2010
231views Solid Modeling» more  GPB 2010»
13 years 2 months ago
Mining Gene Expression Profiles: An Integrated Implementation of Kernel Principal Component Analysis and Singular Value Decompos
The detection of genes that show similar profiles under different experimental conditions is often an initial step in inferring the biological significance of such genes. Visualiz...
Ferran Reverter, Esteban Vegas, Pedro Sánch...
BMCBI
2007
154views more  BMCBI 2007»
13 years 4 months ago
h-Profile plots for the discovery and exploration of patterns in gene expression data with an application to time course data
Background: An ever increasing number of techniques are being used to find genes with similar profiles from microarray studies. Visualization of gene expression profiles can aid t...
Yvonne E. Pittelkow, Susan R. Wilson
GECCO
2004
Springer
104views Optimization» more  GECCO 2004»
13 years 10 months ago
A Genetic Approach for Gene Selection on Microarray Expression Data
Abstract. Microarrays allow simultaneous measurement of the expression levels of thousands of genes in cells under different physiological or disease states. Because the number of...
Yong-Hyuk Kim, Su-Yeon Lee, Byung Ro Moon