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BMCBI
2006
113views more  BMCBI 2006»
13 years 4 months ago
In silico discovery of human natural antisense transcripts
Background: Several high-throughput searches for ppotential natural antisense transcripts (NATs) have been performed recently, but most of the reports were focused on cis type. A ...
Yuan-Yuan Li, Lei Qin, Zong-Ming Guo, Lei Liu, Hao...
BMCBI
2008
120views more  BMCBI 2008»
13 years 4 months ago
Statistical issues in the analysis of Illumina data
Background: Illumina bead-based arrays are becoming increasingly popular due to their high degree of replication and reported high data quality. However, little attention has been...
Mark J. Dunning, Nuno L. Barbosa-Morais, Andy G. L...
BMCBI
2007
166views more  BMCBI 2007»
13 years 4 months ago
PathFinder: mining signal transduction pathway segments from protein-protein interaction networks
Background: A Signal transduction pathway is the chain of processes by which a cell converts an extracellular signal into a response. In most unicellular organisms, the number of ...
Gürkan Bebek, Jiong Yang
BMCBI
2010
84views more  BMCBI 2010»
13 years 4 months ago
A variational Bayes algorithm for fast and accurate multiple locus genome-wide association analysis
Background: The success achieved by genome-wide association (GWA) studies in the identification of candidate loci for complex diseases has been accompanied by an inability to expl...
Benjamin A. Logsdon, Gabriel E. Hoffman, Jason G. ...