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» Methods and Statistics for Combining Motif Match Scores
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TCBB
2010
98views more  TCBB 2010»
13 years 3 days ago
VARUN: Discovering Extensible Motifs under Saturation Constraints
Abstract-The discovery of motifs in biosequences is frequently torn between the rigidity of the model on the one hand and the abundance of candidates on the other. In particular, m...
Alberto Apostolico, Matteo Comin, Laxmi Parida
BMCBI
2008
123views more  BMCBI 2008»
13 years 5 months ago
A tree-based conservation scoring method for short linear motifs in multiple alignments of protein sequences
Background: The structure of many eukaryotic cell regulatory proteins is highly modular. They are assembled from globular domains, segments of natively disordered polypeptides and...
Claudia Chica, Alberto Labarga, Cathryn M. Gould, ...
BMCBI
2005
93views more  BMCBI 2005»
13 years 5 months ago
Computing expectation values for RNA motifs using discrete convolutions
Background: Computational biologists use Expectation values (E-values) to estimate the number of solutions that can be expected by chance during a database scan. Here we focus on ...
André Lambert, Matthieu Legendre, Jean-Fred...
BMCBI
2007
111views more  BMCBI 2007»
13 years 5 months ago
MotifCombinator: a web-based tool to search for combinations of cis-regulatory motifs
Background: A combination of multiple types of transcription factors and cis-regulatory elements is often required for gene expression in eukaryotes, and the combinatorial regulat...
Mamoru Kato, Tatsuhiko Tsunoda
BMCBI
2010
124views more  BMCBI 2010»
13 years 5 months ago
Estimation and efficient computation of the true probability of recurrence of short linear protein sequence motifs in unrelated
Background: Large datasets of protein interactions provide a rich resource for the discovery of Short Linear Motifs (SLiMs) that recur in unrelated proteins. However, existing met...
Norman E. Davey, Richard J. Edwards, Denis C. Shie...