19 search results - page 1 / 4 » MethyCancer: the database of human DNA methylation and cance... |
NAR
2008
13 years 4 months ago
2008
Cancer is ranked as one of the top killers in all human diseases and continues to have a devastating effect on the population around the globe. Current research efforts are aiming...
BMCBI
2008
13 years 4 months ago
2008
Background: DNA methylation is an important epigenetic modification of the genome. Abnormal DNA methylation may result in silencing of tumor suppressor genes and is common in a va...
BIOINFORMATICS
2006
13 years 4 months ago
2006
Motivation: Over 50% of human genes contain CpG islands in their 5'-regions. Methylation patterns of CpG islands are involved in tissue-specific gene expression and regulatio...
BMCBI
2010
13 years 4 months ago
2010
Background: Bisulfite sequencing is a popular method to analyze DNA methylation patterns at high resolution. A region of interest is targeted by PCR and about 20-50 subcloned DNA ...
NAR
2011
2011
NGSmethDB: a database for next-generation sequencing single-cytosine-resolution DNA methylation data
12 years 7 months ago
Next-generation sequencing (NGS) together with bisulphite conversion allows the generation of whole genome methylation maps at single-cytosine resolution. This allows studying the...