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» MethyCancer: the database of human DNA methylation and cance...
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NAR
2008
141views more  NAR 2008»
12 years 1 months ago
MethyCancer: the database of human DNA methylation and cancer
Cancer is ranked as one of the top killers in all human diseases and continues to have a devastating effect on the population around the globe. Current research efforts are aiming...
Ximiao He, Suhua Chang, Jiajie Zhang, Qian Zhao, H...
BMCBI
2008
164views more  BMCBI 2008»
12 years 1 months ago
MeInfoText: associated gene methylation and cancer information from text mining
Background: DNA methylation is an important epigenetic modification of the genome. Abnormal DNA methylation may result in silencing of tumor suppressor genes and is common in a va...
Yu-Ching Fang, Hsuan-Cheng Huang, Hsueh-Fen Juan
BIOINFORMATICS
2006
129views more  BIOINFORMATICS 2006»
12 years 1 months ago
Predicting methylation status of CpG islands in the human brain
Motivation: Over 50% of human genes contain CpG islands in their 5'-regions. Methylation patterns of CpG islands are involved in tissue-specific gene expression and regulatio...
Fang Fang, Shicai Fan, Xuegong Zhang, Michael Q. Z...
BMCBI
2010
155views more  BMCBI 2010»
12 years 1 months ago
BISMA - Fast and accurate bisulfite sequencing data analysis of individual clones from unique and repetitive sequences
Background: Bisulfite sequencing is a popular method to analyze DNA methylation patterns at high resolution. A region of interest is targeted by PCR and about 20-50 subcloned DNA ...
Christian Rohde, Yingying Zhang, Richard Reinhardt...
NAR
2011
172views Computer Vision» more  NAR 2011»
11 years 4 months ago
NGSmethDB: a database for next-generation sequencing single-cytosine-resolution DNA methylation data
Next-generation sequencing (NGS) together with bisulphite conversion allows the generation of whole genome methylation maps at single-cytosine resolution. This allows studying the...
Michael Hackenberg, Guillermo Barturen, José...
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