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» MethyCancer: the database of human DNA methylation and cance...
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BMCBI
2002
109views more  BMCBI 2002»
12 years 1 months ago
Kangaroo - A pattern-matching program for biological sequences
Background: Biologists are often interested in performing a simple database search to identify proteins or genes that contain a well-defined sequence pattern. Many databases do no...
Doron Betel, Christopher W. V. Hogue
BMCBI
2008
128views more  BMCBI 2008»
12 years 2 months ago
Meta-analysis of breast cancer microarray studies in conjunction with conserved cis-elements suggest patterns for coordinate reg
Background: Gene expression measurements from breast cancer (BrCa) tumors are established clinical predictive tools to identify tumor subtypes, identify patients showing poor/good...
David D. Smith, Pål Sætrom, Ola R. Sn&...
BMCBI
2010
103views more  BMCBI 2010»
12 years 2 months ago
A method of predicting changes in human gene splicing induced by genetic variants in context of cis-acting elements
Background: Polymorphic variants and mutations disrupting canonical splicing isoforms are among the leading causes of human hereditary disorders. While there is a substantial evid...
Alexander G. Churbanov, Igor Vorechovsky, Chindo H...
BMCBI
2007
166views more  BMCBI 2007»
12 years 1 months ago
Data handling strategies for high throughput pyrosequencers
Background: New high throughput pyrosequencers such as the 454 Life Sciences GS 20 are capable of massively parallelizing DNA sequencing providing an unprecedented rate of output ...
Gabriele A. Trombetti, Raoul J. P. Bonnal, Ermanno...
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