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BMCBI
2004
120views more  BMCBI 2004»
13 years 4 months ago
Optimal cDNA microarray design using expressed sequence tags for organisms with limited genomic information
Background: Expression microarrays are increasingly used to characterize environmental responses and hostparasite interactions for many different organisms. Probe selection for cD...
Yian A. Chen, David J. Mckillen, Shuyuan Wu, Matth...
BMCBI
2007
129views more  BMCBI 2007»
13 years 5 months ago
HoughFeature, a novel method for assessing drug effects in three-color cDNA microarray experiments
Background: Three-color microarray experiments can be performed to assess drug effects on the genomic scale. The methodology may be useful in shortening the cycle, reducing the co...
Hongya Zhao, Hong Yan
BMCBI
2004
139views more  BMCBI 2004»
13 years 4 months ago
Resolution of large and small differences in gene expression using models for the Bayesian analysis of gene expression levels an
Background: The detection of small yet statistically significant differences in gene expression in spotted DNA microarray studies is an ongoing challenge. Meeting this challenge r...
Jeffrey P. Townsend
BIOINFORMATICS
2006
89views more  BIOINFORMATICS 2006»
13 years 4 months ago
Maximum significance clustering of oligonucleotide microarrays
Affymetrix high-density oligonucleotide microarrays measure expression of DNA transcripts using probesets, i.e. multiple probes per transcript. Usually, these multiple measurement...
Dick de Ridder, Frank J. T. Staal, Jacques J. M. v...
AIME
2009
Springer
13 years 8 months ago
Effect of Background Correction on Cancer Classification with Gene Expression Data
This paper empirically compares six background correction methods aimed at removing unspecific background noise of the overall signal level measured by a scanner across microarrays...
Adelaide Freitas, Gladys Castillo, Ana São ...