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» Mining for Putative Regulatory Elements in the Yeast Genome ...
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BMCBI
2007
147views more  BMCBI 2007»
13 years 5 months ago
Predicting combinatorial binding of transcription factors to regulatory elements in the human genome by association rule mining
Background: Cis-acting transcriptional regulatory elements in mammalian genomes typically contain specific combinations of binding sites for various transcription factors. Althoug...
Xochitl C. Morgan, Shulin Ni, Daniel P. Miranker, ...
PSB
2004
13 years 6 months ago
Motif Discovery in Heterogeneous Sequence Data
This paper introduces the first integrated algorithm designed to discover novel motifs in heterogeneous sequence data, which is comprised of coregulated genes from a single genome...
Amol Prakash, Mathieu Blanchette, Saurabh Sinha, M...
BIODATAMINING
2008
130views more  BIODATAMINING 2008»
13 years 5 months ago
Uncovering mechanisms of transcriptional regulations by systematic mining of cis regulatory elements with gene expression profil
Background: Contrary to the traditional biology approach, where the expression patterns of a handful of genes are studied at a time, microarray experiments enable biologists to st...
Qicheng Ma, Gung-Wei Chirn, Joseph D. Szustakowski...
BMCBI
2010
167views more  BMCBI 2010»
13 years 5 months ago
Inference of sparse combinatorial-control networks from gene-expression data: a message passing approach
Background: Transcriptional gene regulation is one of the most important mechanisms in controlling many essential cellular processes, including cell development, cell-cycle contro...
Marc Bailly-Bechet, Alfredo Braunstein, Andrea Pag...
BMCBI
2006
122views more  BMCBI 2006»
13 years 5 months ago
Computational reconstruction of transcriptional regulatory modules of the yeast cell cycle
Background: A transcriptional regulatory module (TRM) is a set of genes that is regulated by a common set of transcription factors (TFs). By organizing the genome into TRMs, a liv...
Wei-Sheng Wu, Wen-Hsiung Li, Bor-Sen Chen