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BMCBI
2006
183views more  BMCBI 2006»
13 years 4 months ago
Mining gene expression data by interpreting principal components
Background: There are many methods for analyzing microarray data that group together genes having similar patterns of expression over all conditions tested. However, in many insta...
Joseph C. Roden, Brandon W. King, Diane Trout, Ali...
GPB
2010
231views Solid Modeling» more  GPB 2010»
13 years 1 months ago
Mining Gene Expression Profiles: An Integrated Implementation of Kernel Principal Component Analysis and Singular Value Decompos
The detection of genes that show similar profiles under different experimental conditions is often an initial step in inferring the biological significance of such genes. Visualiz...
Ferran Reverter, Esteban Vegas, Pedro Sánch...
BMCBI
2010
144views more  BMCBI 2010»
13 years 4 months ago
Super-sparse principal component analyses for high-throughput genomic data
Background: Principal component analysis (PCA) has gained popularity as a method for the analysis of highdimensional genomic data. However, it is often difficult to interpret the ...
Donghwan Lee, Woojoo Lee, Youngjo Lee, Yudi Pawita...
PAKDD
2005
ACM
164views Data Mining» more  PAKDD 2005»
13 years 10 months ago
Covariance and PCA for Categorical Variables
Covariances from categorical variables are defined using a regular simplex expression for categories. The method follows the variance definition by Gini, and it gives the covaria...
Hirotaka Niitsuma, Takashi Okada
BMCBI
2008
115views more  BMCBI 2008»
13 years 4 months ago
Principal components analysis based methodology to identify differentially expressed genes in time-course microarray data
Background: Time-course microarray experiments are being increasingly used to characterize dynamic biological processes. In these experiments, the goal is to identify genes differ...
Sudhakar Jonnalagadda, Rajagopalan Srinivasan