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» Mining phenotypes for gene function prediction
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BMCBI
2008
129views more  BMCBI 2008»
13 years 4 months ago
Mining phenotypes for gene function prediction
Background: Health and disease of organisms are reflected in their phenotypes. Often, a genetic component to a disease is discovered only after clearly defining its phenotype. In ...
Philip Groth, Bertram Weiss, Hans-Dieter Pohlenz, ...
PKDD
2001
Springer
108views Data Mining» more  PKDD 2001»
13 years 8 months ago
Knowledge Discovery in Multi-label Phenotype Data
The biological sciences are undergoing an explosion in the amount of available data. New data analysis methods are needed to deal with the data. We present work using KDD to analys...
Amanda Clare, Ross D. King
BMCBI
2008
111views more  BMCBI 2008»
13 years 4 months ago
Information-based methods for predicting gene function from systematic gene knock-downs
Background: The rapid annotation of genes on a genome-wide scale is now possible for several organisms using high-throughput RNA interference assays to knock down the expression o...
Matthew T. Weirauch, Christopher K. Wong, Alexandr...
DAGSTUHL
2008
13 years 5 months ago
Mining Phenotypes for Protein Function Prediction
Ulf Leser, Philip Groth, Bertram Weiss, Hans-Diete...
BMCBI
2010
105views more  BMCBI 2010»
13 years 4 months ago
Predicting phenotypic traits of prokaryotes from protein domain frequencies
Background: Establishing the relationship between an organism's genome sequence and its phenotype is a fundamental challenge that remains largely unsolved. Accurately predict...
Thomas Lingner, Stefanie Mühlhausen, Toni Gab...