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» Mining phenotypes for gene function prediction
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BMCBI
2005
134views more  BMCBI 2005»
13 years 4 months ago
Inherited disorder phenotypes: controlled annotation and statistical analysis for knowledge mining from gene lists
Background: Analysis of inherited diseases and their associated phenotypes is of great importance to gain knowledge of underlying genetic interactions and could ultimately give cl...
Marco Masseroli, Osvaldo Galati, Mauro Manzotti, K...
BMCBI
2008
167views more  BMCBI 2008»
13 years 4 months ago
Expression profiles of switch-like genes accurately classify tissue and infectious disease phenotypes in model-based classificat
Background: Large-scale compilation of gene expression microarray datasets across diverse biological phenotypes provided a means of gathering a priori knowledge in the form of ide...
Michael Gormley, Aydin Tozeren
NAR
2008
142views more  NAR 2008»
13 years 4 months ago
CMGSDB: integrating heterogeneous Caenorhabditis elegans data sources using compositional data mining
CMGSDB (Database for Computational Modeling of Gene Silencing) is an integration of heterogeneous data sources about Caenorhabditis elegans with capabilities for compositional dat...
Amrita Pati, Ying Jin, Karsten Klage, Richard F. H...
BMCBI
2010
179views more  BMCBI 2010»
13 years 4 months ago
A semi-supervised learning approach to predict synthetic genetic interactions by combining functional and topological properties
Background: Genetic interaction profiles are highly informative and helpful for understanding the functional linkages between genes, and therefore have been extensively exploited ...
Zhuhong You, Zheng Yin, Kyungsook Han, De-Shuang H...
ICDM
2006
IEEE
127views Data Mining» more  ICDM 2006»
13 years 10 months ago
Predictive Integration of Gene Ontology-Driven Similarity and Functional Interactions
There is a need to develop methods to automatically incorporate prior knowledge to support the prediction and validation of novel functional associations. One such important sourc...
Francisco Azuaje, Haiying Wang, Huiru Zheng, Olivi...