116 search results - page 1 / 24 » Mining protein networks for synthetic genetic interactions |
BMCBI
2008
13 years 4 months ago
2008
Background: The local connectivity and global position of a protein in a protein interaction network are known to correlate with some of its functional properties, including its e...
BMCBI
2010
13 years 4 months ago
2010
Background: Genetic interaction profiles are highly informative and helpful for understanding the functional linkages between genes, and therefore have been extensively exploited ...
BMCBI
2005
13 years 4 months ago
2005
Background: In a genetic interaction, the phenotype of a double mutant differs from the combined phenotypes of the underlying single mutants. When the single mutants have no growt...
BMCBI
2005
13 years 4 months ago
2005
Background: Synthetic lethality experiments identify pairs of genes with complementary function. More direct functional associations (for example greater probability of membership...
KDD
2004
ACM
14 years 5 months ago
2004
ACM
Protein-protein interactions are of great interest to biologists. A variety of high-throughput techniques have been devised, each of which leads to a separate definition of an int...