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» Mixture Model Based Group Inference in Fused Genotype and Ph...
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GFKL
2007
Springer
148views Data Mining» more  GFKL 2007»
13 years 11 months ago
Mixture Model Based Group Inference in Fused Genotype and Phenotype Data
The analysis of genetic diseases has classically been directed towards establishing direct links between cause, a genetic variation, and effect, the observable deviation of phenot...
Benjamin Georgi, M. Anne Spence, Pamela Flodman, A...
JCB
2007
191views more  JCB 2007»
13 years 5 months ago
Bayesian Haplotype Inference via the Dirichlet Process
The problem of inferring haplotypes from genotypes of single nucleotide polymorphisms (SNPs) is essential for the understanding of genetic variation within and among populations, ...
Eric P. Xing, Michael I. Jordan, Roded Sharan
GECCO
2004
Springer
164views Optimization» more  GECCO 2004»
13 years 10 months ago
Fuzzy Dominance Based Multi-objective GA-Simplex Hybrid Algorithms Applied to Gene Network Models
Hybrid algorithms that combine genetic algorithms with the Nelder-Mead simplex algorithm have been effective in solving certain optimization problems. In this article, we apply a s...
Praveen Koduru, Sanjoy Das, Stephen Welch, Judith ...
EVOW
2008
Springer
13 years 6 months ago
Detection of Quantitative Trait Associated Genes Using Cluster Analysis
Abstract. Many efforts have been involved in association study of quantitative phenotypes and expressed genes. The key issue is how to efficiently identify phenotype-associated gen...
Zhenyu Jia, Sha Tang, Dan Mercola, Shizhong Xu
BMCBI
2008
83views more  BMCBI 2008»
13 years 5 months ago
Models of deletion for visualizing bacterial variation: an application to tuberculosis spoligotypes
Background: Molecular typing methods are commonly used to study genetic relationships among bacterial isolates. Many of these methods have become standardized and produce portable...
Josephine F. Reyes, Andrew R. Francis, Mark M. Tan...