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» Model Based Analysis of Signaling Pathways
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GG
2004
Springer
13 years 11 months ago
Analysis of Metabolic Pathways by Graph Transformation
Biochemical pathways, such as metabolic, regulatory, and signal transduction pathways, constitute complex networks of functional and physical interactions between molecular species...
Francesc Rosselló, Gabriel Valiente
BMCBI
2011
13 years 1 months ago
Context-dependent transcriptional regulations between signal transduction pathways
Background: Cells coordinate their metabolism, proliferation, and cellular communication according to environmental cues through signal transduction. Because signal transduction h...
Sohyun Hwang, Sangwoo Kim, Heesung Shin, Doheon Le...
AIME
2009
Springer
13 years 7 months ago
Semantic Web-Based Modeling of Clinical Pathways Using the UML Activity Diagrams and OWL-S
: Clinical Pathways can be viewed as workflows, comprising an ordering of activities with associated execution constraints. Workflow models allow formal representation, analysis an...
Ali Daniyal, Syed Sibte Raza Abidi
BMCBI
2005
109views more  BMCBI 2005»
13 years 6 months ago
Automation of gene assignments to metabolic pathways using high-throughput expression data
Background: Accurate assignment of genes to pathways is essential in order to understand the functional role of genes and to map the existing pathways in a given genome. Existing ...
Liviu Popescu, Golan Yona
BMCBI
2010
126views more  BMCBI 2010»
13 years 3 months ago
PETALS: Proteomic Evaluation and Topological Analysis of a mutated Locus' Signaling
Background: Colon cancer is driven by mutations in a number of genes, the most notorious of which is Apc. Though much of Apc's signaling has been mechanistically identified o...
Gürkan Bebek, Vishal Patel, Mark R. Chance