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JCB
2002
131views more  JCB 2002»
13 years 4 months ago
Modeling and Simulation of Genetic Regulatory Systems: A Literature Review
In order to understand the functioning of organisms on the molecular level, we need to know which genes are expressed, when and where in the organism, and to which extent. The reg...
Hidde de Jong
GECCO
2005
Springer
149views Optimization» more  GECCO 2005»
13 years 10 months ago
There's more to a model than code: understanding and formalizing in silico modeling experience
Mapping biology into computation has both a domain specific aspect – biological theory – and a methodological aspect – model development. Computational modelers have implici...
Janet Wiles, Nicholas Geard, James Watson, Kai Wil...
VISUALIZATION
2002
IEEE
13 years 9 months ago
GeneVis: Visualization Tools for Genetic Regulatory Network Dynamics
GeneVis provides a visual environment for exploring the dynamics of genetic regulatory networks. At present time, genetic regulation is the focus of intensive research worldwide, ...
Charles A. H. Baker, M. Sheelagh T. Carpendale, Pr...
HYBRID
2001
Springer
13 years 9 months ago
Hybrid Modeling and Simulation of Biomolecular Networks
Abstract. In a biological cell, cellular functions and the genetic regulatory apparatus are implemented and controlled by a network of chemical reactions in which regulatory protei...
Rajeev Alur, Calin Belta, Franjo Ivancic
EUROGP
2006
Springer
140views Optimization» more  EUROGP 2006»
13 years 8 months ago
Evolving Noisy Oscillatory Dynamics in Genetic Regulatory Networks
We introduce a genetic programming (GP) approach for evolving genetic networks that demonstrate desired dynamics when simulated as a discrete stochastic process. Our representation...
André Leier, P. Dwight Kuo, Wolfgang Banzha...