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» Modeling the Progression and Treatment of HIV
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WSC
2004
13 years 6 months ago
Modeling the Progression and Treatment of HIV
Current treatment of HIV patients is based on various guidelines that have changed with the advent of newer antiretroviral therapies and the emergence of resistance to them. Howev...
Steven M. Shechter, Andrew J. Schaefer, R. Scott B...
LSMS
2007
Springer
13 years 11 months ago
AOC-by-Self-discovery Modeling and Simulation for HIV
Among HIV, immune cell and drug, exhibit interactions that are usually not well understood and as a result, cannot be accurately modeled. In this paper, Modeling by AOC is to under...
Chunxiao Zhao, Ning Zhong, Ying Hao
BMCBI
2010
104views more  BMCBI 2010»
13 years 4 months ago
Formal reasoning on qualitative models of coinfection of HIV and Tuberculosis and HAART therapy
Background: Several diseases, many of which nowadays pandemic, consist of multifactorial pathologies. Paradigmatic examples come from the immune response to pathogens, in which ca...
Anil Sorathiya, Andrea Bracciali, Pietro Liò...
BMCBI
2008
92views more  BMCBI 2008»
13 years 4 months ago
Proteochemometric modeling of HIV protease susceptibility
Background: A major obstacle in treatment of HIV is the ability of the virus to mutate rapidly into drug-resistant variants. A method for predicting the susceptibility of mutated ...
Maris Lapinsh, Martin Eklund, Ola Spjuth, Peteris ...
GECCO
2005
Springer
127views Optimization» more  GECCO 2005»
13 years 10 months ago
Sufficiency verification of HIV-1 pathogenesis based on multi-agent simulation
Researchers of HIV-1 are today, still unable to determine exactly the biological mechanisms that cause AIDS. Various mechanisms have been hypothesized and their existences have be...
Zaiyi Guo, Hann Kwang Han, Joc Cing Tay