In biological sequence processing, Multiple Sequence Alignment (MSA) techniques capture information about long-distance dependencies and the three-dimensional structure of protein ...
Background: Alignments of homologous DNA sequences are crucial for comparative genomics and phylogenetic analysis. However, multiple alignment represents a computationally difficu...
Background: Sequence alignment is a common tool in bioinformatics and comparative genomics. It is generally assumed that multiple sequence alignment yields better results than pai...
Multiple sequence alignments are essential in homology inference, structure modeling, functional prediction and phylogenetic analysis. We developed a web server that constructs mu...
Jimin Pei, Bong-Hyun Kim, Ming Tang, Nick V. Grish...
Background: Automated software tools for multiple alignment often fail to produce biologically meaningful results. In such situations, expert knowledge can help to improve the qua...
Burkhard Morgenstern, Sonja J. Prohaska, Dirk P&ou...