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BMCBI
2011
13 years 15 days ago
Removing Noise From Pyrosequenced Amplicons
Background: In many environmental genomics applications a homologous region of DNA from a diverse sample is first amplified by PCR and then sequenced. The next generation sequenci...
Christopher Quince, Anders Lanzén, Russell ...
BMCBI
2011
12 years 9 months ago
Inference of Chromosome-Specific Copy Numbers Using Population Haplotypes
Background: Using microarray and sequencing platforms, a large number of copy number variations (CNVs) have been identified in humans. In practice, because our human genome is a d...
Yao-Ting Huang, Min-Han Wu
BMCBI
2011
12 years 9 months ago
New Words in Human Mutagenesis
Background: The substitution rates within different nucleotide contexts are subject to varying levels of bias. The most well known example of such bias is the excess of C to T (C ...
Alexander Y. Panchin, Sergey I. Mitrofanov, Andrei...
CHI
2011
ACM
12 years 9 months ago
No clicks, no problem: using cursor movements to understand and improve search
Understanding how people interact with search engines is important in improving search quality. Web search engines typically analyze queries and clicked results, but these actions...
Jeff Huang, Ryen W. White, Susan T. Dumais
BMCBI
2008
128views more  BMCBI 2008»
13 years 5 months ago
Meta-analysis of breast cancer microarray studies in conjunction with conserved cis-elements suggest patterns for coordinate reg
Background: Gene expression measurements from breast cancer (BrCa) tumors are established clinical predictive tools to identify tumor subtypes, identify patients showing poor/good...
David D. Smith, Pål Sætrom, Ola R. Sn&...