: If we consider the regulatory networks used in systems biology (especially in neural and genetic networks), we observe certain regularities in their architecture, namely the occu...
Adrien Elena, Hedi Ben Amor, N. Glade, Jacques Dem...
Background: Several motif detection algorithms have been developed to discover overrepresented motifs in sets of coexpressed genes. However, in a noisy gene list, the number of ge...
Pieter Monsieurs, Gert Thijs, Abeer A. Fadda, Sigr...
Background: Discovering approximately repeated patterns, or motifs, in biological sequences is an important and widely-studied problem in computational molecular biology. Most fre...
Linear motifs are short segments of multidomain proteins that provide regulatory functions independently of protein tertiary structure. Much of intracellular signalling passes thr...
Cathryn M. Gould, Francesca Diella, Allegra Via, P...
We present a novel classification-based algorithm called GeneClass for learning to predict gene regulatory response. Our approach is motivated by the hypothesis that in simple orga...
Manuel Middendorf, Anshul Kundaje, Chris Wiggins, ...