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» Multi-Body Interactions within the Graph of Protein Structur...
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BMCBI
2007
227views more  BMCBI 2007»
13 years 5 months ago
Growing functional modules from a seed protein via integration of protein interaction and gene expression data
Background: Nowadays modern biology aims at unravelling the strands of complex biological structures such as the protein-protein interaction (PPI) networks. A key concept in the o...
Ioannis A. Maraziotis, Konstantina Dimitrakopoulou...
BMCBI
2010
178views more  BMCBI 2010»
13 years 5 months ago
An improved method for scoring protein-protein interactions using semantic similarity within the Gene Ontology
Background: Semantic similarity measures are useful to assess the physiological relevance of protein-protein interactions (PPIs). They quantify similarity between proteins based o...
Shobhit Jain, Gary D. Bader
AINA
2009
IEEE
14 years 3 days ago
The Small-World Model for Amino Acid Interaction Networks
—In this paper we introduce the notion of protein interaction network. This is a graph whose vertices are the protein’s amino acids and whose edges are the interactions between...
Omar Gaci, Stefan Balev
BMCBI
2005
253views more  BMCBI 2005»
13 years 5 months ago
The Use of Edge-Betweenness Clustering to Investigate Biological Function in Protein Interaction Networks
Background: This paper describes an automated method for finding clusters of interconnected proteins in protein interaction networks and retrieving protein annotations associated ...
Ruth Dunn, Frank Dudbridge, Christopher M. Sanders...
BMCBI
2010
95views more  BMCBI 2010»
13 years 5 months ago
Protein structure modelling and evaluation based on a 4-distance description of side-chain interactions
Background: Accurate evaluation and modelling of residue-residue interactions within and between proteins is a key aspect of computational structure prediction including homology ...
Vladimir Potapov, Mati Cohen, Yuval Inbar, Gideon ...