Abstract. The hydrophobic-polar (HP) model for protein structure preabstracts the fact that hydrophobic interactions are a dominant force in the protein folding process. This model...
Mario Garza-Fabre, Eduardo Rodriguez-Tello, Gregor...
Abstract—Protein structure prediction is the problem of finding the functional conformation of a protein given only its amino uence. The HP lattice model is an abstract formulat...
Mario Garza-Fabre, Eduardo Rodriguez-Tello, Gregor...
Background: The ab initio protein folding problem consists of predicting protein tertiary structure from a given amino acid sequence by minimizing an energy function; it is one of...
This paper presents a memetic algorithm with self-adaptive local search, applied to protein structure prediction in an HP, cubiclattice model. Besides describing in detail how the ...
In this paper, we propose a simple genetic algorithm for finding the optimal conformation of a protein using the three-dimensional square HP model. A backtracking procedure is use...