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BMCBI
2008
147views more  BMCBI 2008»
13 years 5 months ago
Transmembrane helix prediction using amino acid property features and latent semantic analysis
Background: Prediction of transmembrane (TM) helices by statistical methods suffers from lack of sufficient training data. Current best methods use hundreds or even thousands of f...
Madhavi Ganapathiraju, Narayanas Balakrishnan, Raj...
BMCBI
2010
114views more  BMCBI 2010»
13 years 5 months ago
An integrative modular approach to systematically predict gene-phenotype associations
Background: Complex human diseases are often caused by multiple mutations, each of which contributes only a minor effect to the disease phenotype. To study the basis for these com...
Michael R. Mehan, Juan Nunez-Iglesias, Chao Dai, M...
BMCBI
2007
165views more  BMCBI 2007»
13 years 5 months ago
Ab initio identification of human microRNAs based on structure motifs
Background: MicroRNAs (miRNAs) are short, non-coding RNA molecules that are directly involved in post-transcriptional regulation of gene expression. The mature miRNA sequence bind...
Markus Brameier, Carsten Wiuf
CATE
2004
190views Education» more  CATE 2004»
13 years 7 months ago
Enhancing Online Learning Performance: An Application of Data Mining Methods
Recently web-based educational systems collect vast amounts of data on user patterns, and data mining methods can be applied to these databases to discover interesting associations...
Behrouz Minaei-Bidgoli, Gerd Kortemeyer, William F...
BMCBI
2007
142views more  BMCBI 2007»
13 years 5 months ago
Improving model construction of profile HMMs for remote homology detection through structural alignment
Background: Remote homology detection is a challenging problem in Bioinformatics. Arguably, profile Hidden Markov Models (pHMMs) are one of the most successful approaches in addre...
Juliana S. Bernardes, Alberto M. R. Dávila,...