Background: Prediction of transmembrane (TM) helices by statistical methods suffers from lack of sufficient training data. Current best methods use hundreds or even thousands of f...
Background: Complex human diseases are often caused by multiple mutations, each of which contributes only a minor effect to the disease phenotype. To study the basis for these com...
Michael R. Mehan, Juan Nunez-Iglesias, Chao Dai, M...
Background: MicroRNAs (miRNAs) are short, non-coding RNA molecules that are directly involved in post-transcriptional regulation of gene expression. The mature miRNA sequence bind...
Recently web-based educational systems collect vast amounts of data on user patterns, and data mining methods can be applied to these databases to discover interesting associations...
Behrouz Minaei-Bidgoli, Gerd Kortemeyer, William F...
Background: Remote homology detection is a challenging problem in Bioinformatics. Arguably, profile Hidden Markov Models (pHMMs) are one of the most successful approaches in addre...