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BMCBI
2010
106views more  BMCBI 2010»
13 years 4 months ago
Multiple structure alignment and consensus identification for proteins
Background: An algorithm is presented to compute a multiple structure alignment for a set of proteins and to generate a consensus (pseudo) protein which captures common substructu...
Ivaylo Ilinkin, Jieping Ye, Ravi Janardan
BMCBI
2005
132views more  BMCBI 2005»
13 years 4 months ago
Kalign - an accurate and fast multiple sequence alignment algorithm
Background: The alignment of multiple protein sequences is a fundamental step in the analysis of biological data. It has traditionally been applied to analyzing protein families f...
Timo Lassmann, Erik L. L. Sonnhammer
BMCBI
2004
96views more  BMCBI 2004»
13 years 4 months ago
Identification of regions in multiple sequence alignments thermodynamically suitable for targeting by consensus oligonucleotides
Background: Computer programs for the generation of multiple sequence alignments such as "Clustal W" allow detection of regions that are most conserved among many sequen...
Olga V. Matveeva, Brian T. Foley, Vladimir A. Nemt...
NAR
2008
152views more  NAR 2008»
13 years 4 months ago
PROMALS3D web server for accurate multiple protein sequence and structure alignments
Multiple sequence alignments are essential in computational sequence and structural analysis, with applications in homology detection, structure modeling, function prediction and ...
Jimin Pei, Ming Tang, Nick V. Grishin
BMCBI
2010
132views more  BMCBI 2010»
13 years 4 months ago
dConsensus: a tool for displaying domain assignments by multiple structure-based algorithms and for construction of a consensus
Background: Partitioning of a protein into structural components, known as domains, is an important initial step in protein classification and for functional and evolutionary stud...
Kieran Alden, Stella Veretnik, Philip E. Bourne