Background: The Thymidine kinase (Tk) mutants generated from the widely used L5178Y mouse lymphoma assay fall into two categories, small colony and large colony. Cells from the la...
Tao Han, Jianyong Wang, Weida Tong, Martha M. Moor...
Background: Activated Protein C (ProC) is an anticoagulant plasma serine protease which also plays an important role in controlling inflammation and cell proliferation. Several mu...
Pasqualina D'Ursi, Francesca Marino, Andrea Caprer...
Background: The ability to design thermostable proteins is theoretically important and practically useful. Robust and accurate algorithms, however, remain elusive. One critical pr...
Fault insertion based techniqueshave been used for measuring test adequacy and testability of programs. Mutation analysis inserts faults into a program with the goal of creating m...
Roger T. Alexander, James M. Bieman, Sudipto Ghosh...
Abstract. The work of Voas and colleagues has introduced, refined and applied the propagation, infection and execution (PIE) analysis technique for measuring testability of program...
Zuhoor A. Al-Khanjari, Martin R. Woodward, Haider ...