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» Mutation Analysis Using Mutant Schemata
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BMCBI
2006
102views more  BMCBI 2006»
13 years 5 months ago
Microarray analysis distinguishes differential gene expression patterns from large and small colony Thymidine kinase mutants of
Background: The Thymidine kinase (Tk) mutants generated from the widely used L5178Y mouse lymphoma assay fall into two categories, small colony and large colony. Cells from the la...
Tao Han, Jianyong Wang, Weida Tong, Martha M. Moor...
BMCBI
2007
155views more  BMCBI 2007»
13 years 5 months ago
ProCMD: a database and 3D web resource for protein C mutants
Background: Activated Protein C (ProC) is an anticoagulant plasma serine protease which also plays an important role in controlling inflammation and cell proliferation. Several mu...
Pasqualina D'Ursi, Francesca Marino, Andrea Caprer...
BMCBI
2010
104views more  BMCBI 2010»
13 years 5 months ago
A novel scoring function for discriminating hyperthermophilic and mesophilic proteins with application to predicting relative th
Background: The ability to design thermostable proteins is theoretically important and practically useful. Robust and accurate algorithms, however, remain elusive. One critical pr...
Yunqi Li, C. Russell Middaugh, Jianwen Fang
ISSRE
2002
IEEE
13 years 10 months ago
Mutation of Java Objects
Fault insertion based techniqueshave been used for measuring test adequacy and testability of programs. Mutation analysis inserts faults into a program with the goal of creating m...
Roger T. Alexander, James M. Bieman, Sudipto Ghosh...
SQJ
2002
90views more  SQJ 2002»
13 years 5 months ago
Critical Analysis of the PIE Testability Technique
Abstract. The work of Voas and colleagues has introduced, refined and applied the propagation, infection and execution (PIE) analysis technique for measuring testability of program...
Zuhoor A. Al-Khanjari, Martin R. Woodward, Haider ...