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» NITPICK: peak identification for mass spectrometry data
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BMCBI
2010
140views more  BMCBI 2010»
13 years 5 months ago
Quantification and deconvolution of asymmetric LC-MS peaks using the bi-Gaussian mixture model and statistical model selection
Background: Liquid chromatography-mass spectrometry (LC-MS) is one of the major techniques for the quantification of metabolites in complex biological samples. Peak modeling is on...
Tianwei Yu, Hesen Peng
CANDC
2006
ACM
13 years 5 months ago
Detecting and aligning peaks in mass spectrometry data with applications to MALDI
In this paper, we address the peak detection and alignment problem in the analysis of mass spectrometry data. To deal with the peak redundancy problem existing in the MALDI data a...
Weichuan Yu, Baolin Wu, Ning Lin, Kathy Stone, Ken...
VIS
2005
IEEE
204views Visualization» more  VIS 2005»
14 years 6 months ago
Differential Protein Expression Analysis via Liquid-Chromatography/Mass-Spectrometry Data Visualization
Differential protein expression analysis is one of the main challenges in proteomics. It denotes the search for proteins, whose encoding genes are differentially expressed under a...
Lars Linsen, Julia Löcherbach, Matthias Berth...
BMCBI
2010
74views more  BMCBI 2010»
13 years 5 months ago
Correcting for the effects of natural abundance in stable isotope resolved metabolomics experiments involving ultra-high resolut
Background: Stable isotope tracing with ultra-high resolution Fourier transform-ion cyclotron resonance-mass spectrometry (FT-ICR-MS) can provide simultaneous determination of hun...
Hunter N. B. Moseley
BMCBI
2005
121views more  BMCBI 2005»
13 years 5 months ago
Quality control and quality assessment of data from surface-enhanced laser desorption/ionization (SELDI) time-of flight (TOF) ma
Background: Proteomic profiling of complex biological mixtures by the ProteinChip technology of surfaceenhanced laser desorption/ionization time-of-flight (SELDI-TOF) mass spectro...
Huixiao Hong, Yvonne P. Dragan, Joshua Epstein, Ca...