4 search results - page 1 / 1 » Nanopore Detector based analysis of single-molecule conforma... |
BMCBI
2006
2006
Nanopore Detector based analysis of single-molecule conformational kinetics and binding interactions
13 years 4 months ago
Background: A Nanopore Detector provides a means to transduce single molecule events into observable channel current changes. Nanopore-based detection can report directly, or indi...
BMCBI
2007
13 years 4 months ago
2007
Background: The UNO/RIC Nanopore Detector provides a new way to study the binding and conformational changes of individual antibodies. Many critical questions regarding antibody f...
BMCBI
2006
13 years 4 months ago
2006
Background: Channel current feature extraction methods, using Hidden Markov Models (HMMs) have been designed for tracking individual-molecule conformational changes. This informat...
BMCBI
2007
13 years 4 months ago
2007
Background: Ionic current blockade signal processing, for use in nanopore detection, offers a promising new way to analyze single molecule properties, with potential implications ...