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» New Bounds for Motif Finding in Strong Instances
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BMCBI
2010
86views more  BMCBI 2010»
13 years 5 months ago
Fast motif recognition via application of statistical thresholds
Background: Improving the accuracy and efficiency of motif recognition is an important computational challenge that has application to detecting transcription factor binding sites...
Christina Boucher, James King
BMCBI
2006
98views more  BMCBI 2006»
13 years 5 months ago
Scanning sequences after Gibbs sampling to find multiple occurrences of functional elements
Background: Many DNA regulatory elements occur as multiple instances within a target promoter. Gibbs sampling programs for finding DNA regulatory elements de novo can be prohibiti...
Kannan Tharakaraman, Leonardo Mariño-Ram&ia...
BMCBI
2008
98views more  BMCBI 2008»
13 years 5 months ago
MTAP: The Motif Tool Assessment Platform
Background: In recent years, substantial effort has been applied to de novo regulatory motif discovery. At this time, more than 150 software tools exist to detect regulatory bindi...
Daniel Quest, Kathryn Dempsey, Mohammad Shafiullah...
SPIRE
2009
Springer
13 years 10 months ago
Faster Algorithms for Sampling and Counting Biological Sequences
Abstract. A set of sequences S is pairwise bounded if the Hamming distance between any pair of sequences in S is at most 2d. The Consensus Sequence problem aims to discern between ...
Christina Boucher
GECCO
2006
Springer
151views Optimization» more  GECCO 2006»
13 years 9 months ago
Neighbourhood searches for the bounded diameter minimum spanning tree problem embedded in a VNS, EA, and ACO
We consider the Bounded Diameter Minimum Spanning Tree problem and describe four neighbourhood searches for it. They are used as local improvement strategies within a variable nei...
Martin Gruber, Jano I. van Hemert, Günther R....