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» Non-additivity in protein-DNA binding
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BMCBI
2010
95views more  BMCBI 2010»
13 years 4 months ago
An effective approach for identification of in vivo protein-DNA binding sites from paired-end ChIP-Seq data
Background: ChIP-Seq, which combines chromatin immunoprecipitation (ChIP) with high-throughput massively parallel sequencing, is increasingly being used for identification of prot...
Congmao Wang, Jie Xu, Dasheng Zhang, Zoe A. Wilson...
BMCBI
2010
167views more  BMCBI 2010»
13 years 4 months ago
Creating PWMs of transcription factors using 3D structure-based computation of protein-DNA free binding energies
Background: Knowledge of transcription factor-DNA binding patterns is crucial for understanding gene transcription. Numerous DNA-binding proteins are annotated as transcription fa...
Denitsa Alamanova, Philip Stegmaier, Alexander E. ...
BIOINFORMATICS
2005
46views more  BIOINFORMATICS 2005»
13 years 4 months ago
Non-additivity in protein-DNA binding
Ruadhan A. O'Flanagan, Guillaume Paillard, Richard...
BMCBI
2006
110views more  BMCBI 2006»
13 years 4 months ago
Design of a combinatorial DNA microarray for protein-DNA interaction studies
Background: Discovery of precise specificity of transcription factors is an important step on the way to understanding the complex mechanisms of gene regulation in eukaryotes. Rec...
Julian Mintseris, Michael B. Eisen
NAR
2011
196views Computer Vision» more  NAR 2011»
12 years 7 months ago
UniPROBE, update 2011: expanded content and search tools in the online database of protein-binding microarray data on protein-DN
The Universal PBM Resource for OligonucleotideBinding Evaluation (UniPROBE) database is a centralized repository of information on the DNAbinding preferences of proteins as determ...
Kimberly Robasky, Martha L. Bulyk