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BMCBI
2006
132views more  BMCBI 2006»
13 years 4 months ago
Genome-wide DNA polymorphism analyses using VariScan
Background: DNA sequence polymorphisms analysis can provide valuable information on the evolutionary forces shaping nucleotide variation, and provides an insight into the function...
Stephan Hutter, Albert J. Vilella, Julio Rozas
BMCBI
2010
153views more  BMCBI 2010»
13 years 4 months ago
Pash 3.0: A versatile software package for read mapping and integrative analysis of genomic and epigenomic variation using massi
Background: Massively parallel sequencing readouts of epigenomic assays are enabling integrative genome-wide analyses of genomic and epigenomic variation. Pash 3.0 performs sequen...
Cristian Coarfa, Fuli Yu, Christopher A. Miller, Z...
BMCBI
2008
136views more  BMCBI 2008»
13 years 4 months ago
GPAT: Retrieval of genomic annotation from large genomic position datasets
Background: Recent genome wide transcription factor binding site or chromatin modification mapping analysis techniques, such as chromatin immunoprecipitation (ChIP) linked to DNA ...
Arnaud Krebs, Mattia Frontini, Làszlò...
FPL
2003
Springer
128views Hardware» more  FPL 2003»
13 years 10 months ago
Case Study of a Functional Genomics Application
Although microarrays are already having a tremendous impact on biomedical science, they still present great computational challenges. We examine a particular problem involving the...
Tom Van Court, Martin C. Herbordt, Richard J. Bart...
NAR
1998
229views more  NAR 1998»
13 years 4 months ago
GDB: the Human Genome Database
The Genome Database (GDB, http://www.gdb.org ) is a public repository of data on human genes, clones, STSs, polymorphisms and maps. GDB entries are highly cross-linked to each oth...
Stanley Letovsky, Robert W. Cottingham, Christophe...