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BMCBI
2008
156views more  BMCBI 2008»
13 years 5 months ago
Chromhome: A rich internet application for accessing comparative chromosome homology maps
Background: Comparative genomics has become a significant research area in recent years, following the availability of a number of sequenced genomes. The comparison of genomes is ...
Sridevi Nagarajan, Willem Rens, James Stalker, Ton...
BMCBI
2008
105views more  BMCBI 2008»
13 years 5 months ago
Using the longest significance run to estimate region-specific p-values in genetic association mapping studies
Background: Association testing is a powerful tool for identifying disease susceptibility genes underlying complex diseases. Technological advances have yielded a dramatic increas...
Ie-Bin Lian, Yi-Hsien Lin, Ying-Chao Lin, Hsin-Cho...
BMCBI
2008
171views more  BMCBI 2008»
13 years 5 months ago
Fuzzy association rules for biological data analysis: A case study on yeast
Background: Last years' mapping of diverse genomes has generated huge amounts of biological data which are currently dispersed through many databases. Integration of the info...
Francisco J. Lopez, Armando Blanco, Fernando Garci...
JCB
2000
137views more  JCB 2000»
13 years 5 months ago
NOTUNG: A Program for Dating Gene Duplications and Optimizing Gene Family Trees
Large scale gene duplication is a major force driving the evolution of genetic functional innovation. Whole genome duplications are widely believed to have played an important rol...
Kevin Chen, Dannie Durand, Martin Farach-Colton
BMCBI
2005
102views more  BMCBI 2005»
13 years 5 months ago
Genome-wide identification of the regulatory targets of a transcription factor using biochemical characterization and computatio
Background: A major challenge in computational genomics is the development of methodologies that allow accurate genome-wide prediction of the regulatory targets of a transcription...
Emmitt R. Jolly, Chen-Shan Chin, Ira Herskowitz, H...