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BMCBI
2010
216views more  BMCBI 2010»
12 years 11 months ago
Bayesian Inference of the Number of Factors in Gene-Expression Analysis: Application to Human Virus Challenge Studies
Background: Nonparametric Bayesian techniques have been developed recently to extend the sophistication of factor models, allowing one to infer the number of appropriate factors f...
Bo Chen, Minhua Chen, John William Paisley, Aimee ...
ICA
2007
Springer
13 years 8 months ago
Infinite Sparse Factor Analysis and Infinite Independent Components Analysis
Abstract. A nonparametric Bayesian extension of Independent Components Analysis (ICA) is proposed where observed data Y is modelled as a linear superposition, G, of a potentially i...
David Knowles, Zoubin Ghahramani
BMCBI
2007
143views more  BMCBI 2007»
13 years 4 months ago
Factor analysis for gene regulatory networks and transcription factor activity profiles
Background: Most existing algorithms for the inference of the structure of gene regulatory networks from gene expression data assume that the activity levels of transcription fact...
Iosifina Pournara, Lorenz Wernisch
BIOINFORMATICS
2005
151views more  BIOINFORMATICS 2005»
13 years 4 months ago
Differential and trajectory methods for time course gene expression data
Motivation: The issue of high dimensionality in microarray data has been, and remains, a hot topic in statistical and computational analysis. Efficient gene filtering and differen...
Yulan Liang, Bamidele Tayo, Xueya Cai, Arpad Kelem...