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JMLR
2010
159views more  JMLR 2010»
13 years 16 days ago
Inference of Sparse Networks with Unobserved Variables. Application to Gene Regulatory Networks
Networks are becoming a unifying framework for modeling complex systems and network inference problems are frequently encountered in many fields. Here, I develop and apply a gener...
Nikolai Slavov
EJASP
2010
132views more  EJASP 2010»
13 years 19 days ago
Uncovering Transcriptional Regulatory Networks by Sparse Bayesian Factor Model
The problem of uncovering transcriptional regulation by transcription factors (TFs) based on microarray data is considered. A novel Bayesian sparse correlated rectified factor mod...
Jia Meng, Jianqiu Zhang, Yuan (Alan) Qi, Yidong Ch...
BMCBI
2008
128views more  BMCBI 2008»
13 years 5 months ago
Finding sequence motifs with Bayesian models incorporating positional information: an application to transcription factor bindin
Background: Biologically active sequence motifs often have positional preferences with respect to a genomic landmark. For example, many known transcription factor binding sites (T...
Nak-Kyeong Kim, Kannan Tharakaraman, Leonardo Mari...
AAAI
2010
13 years 7 months ago
Bayesian Matrix Factorization with Side Information and Dirichlet Process Mixtures
Matrix factorization is a fundamental technique in machine learning that is applicable to collaborative filtering, information retrieval and many other areas. In collaborative fil...
Ian Porteous, Arthur Asuncion, Max Welling
BMCBI
2010
172views more  BMCBI 2010»
13 years 23 days ago
Nonparametric identification of regulatory interactions from spatial and temporal gene expression data
Background: The correlation between the expression levels of transcription factors and their target genes can be used to infer interactions within animal regulatory networks, but ...
Anil Aswani, Soile V. E. Keränen, James Brown...