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BMCBI
2007
130views more  BMCBI 2007»
13 years 4 months ago
A robust measure of correlation between two genes on a microarray
Background: The underlying goal of microarray experiments is to identify gene expression patterns across different experimental conditions. Genes that are contained in a particula...
Johanna S. Hardin, Aya Mitani, Leanne Hicks, Brian...
BMCBI
2004
113views more  BMCBI 2004»
13 years 4 months ago
Leveraging two-way probe-level block design for identifying differential gene expression with high-density oligonucleotide array
Background: To identify differentially expressed genes across experimental conditions in oligonucleotide microarray experiments, existing statistical methods commonly use a summar...
Leah Barrera, Chris Benner, Yong-Chuan Tao, Elizab...
BMCBI
2007
148views more  BMCBI 2007»
13 years 4 months ago
Computation of significance scores of unweighted Gene Set Enrichment Analyses
Background: Gene Set Enrichment Analysis (GSEA) is a computational method for the statistical evaluation of sorted lists of genes or proteins. Originally GSEA was developed for in...
Andreas Keller, Christina Backes, Hans-Peter Lenho...
BMCBI
2006
91views more  BMCBI 2006»
13 years 4 months ago
In silico identification of putative promoter motifs of White Spot Syndrome Virus
Background: White Spot Syndrome Virus, a member of the virus family Nimaviridae, is a large dsDNA virus infecting shrimp and other crustacean species. Although limited information...
Hendrik Marks, Xin-Ying Ren, Hans Sandbrink, Mari&...
BMCBI
2011
12 years 11 months ago
Shape-based peak identification for ChIP-Seq
Background: The identification of binding targets for proteins using ChIP-Seq has gained popularity as an alternative to ChIP-chip. Sequencing can, in principle, eliminate artifac...
Valerie Hower, Steven N. Evans, Lior Pachter